Swapping motherboards...

Greetings! My file server has a K6-2 motherboard that I'm going to replace with an Athlon motherboard. I have the system drive connected to the motherboard IDE controller, and two drives in a software RAID-1 configuration connected to a IDE controller card. I'm using SuSE 9.1 with the default kernal. In the past, I have swapped motherboards of similar types (e.g., Socket 7) without complications. Are there any special issues when swapping motherboards of different types? Thanks! Christopher Reimer