sharing /home between different linuxes

Hello, I am in the process of setting up a multi-boot system, where I may have Suse, Ubuntu and possibly another variant of linux. (I am in learning mode) Will there be any problems if I mount /home on one partition (say on /dev/hda5), and use that partition as /home for all of the flavours of linux? Would there be conflicts when installing one system if another already has its /home on /dev/hda5 or when upgrading? i.e. will the upgrade or install wipe the existing /home? Would there be any problems with using Gnome on one linux and kde on another? Would it be OK to share say Thunderbird email between the different flavours even if the versions of Thurderbird differed slightly? Is it a good idea? John