Comment # 15 on bug 860729 from Takashi Iwai

With systemd, you'd just need to create a shell script in
/usr/lib/systemd/system-sleep/*.  For example, create a file
/usr/lib/systemd/system-sleep/01-ohci-hack, containing:

#!/bin/sh
case "$1" in
pre)
  /usr/sbin/modprobe -r ohci_pci;;
post)
  /usr/sbin/modprobe ohci_pci;;
esac
exit 0

.... and do "chmod +x /usr/lib/systemd/system-sleep/01-ohci-hack".
Please confirm whether this workaround is still valid.

Also, check the contents of /proc/acpi/wakeup.  If any of the USB-related
entries is enabled, try to disable by writing the device to the proc file.  For
example, if USB1 has the enabled status, run like:
   echo -n USB1 > /proc/acpi/wakeup
Then check the content of the proc file again to see that it's disabled now.

Try the latter check before trying the systemd hook.