Problem solved (in a way), thanks to a bug report on virtualbox.org: https://www.virtualbox.org/ticket/21312 I reduced memory on the Win7 VM to 2048 MB and fired up one scanner, then the other. Both worked properly in the Win7 VM! I need only remember to reduce memory to 2048 MB when I want to scan something. This feels like a stopgap solution, so I won't close this bug report. Please feel free to close it as solved, if you think it should be closed. Please also let me know if you think I should post a thread with this information on the virtualbox forum.