In general, everything that I tried, does not help, rebuild the kernel without patches, compile the kernel from appstrim, disable spectre, rebuild gnome-shell, gjs, xorg, mesa, mutter, try kernel-vanilla, it all partially solved the problem, but still not as it should be. The best option is disable Hyper threading, only on my laptop I have no such opportunity, on my PC it is possible,. installed openSUSE Leap, with enabled Hyper threading the problem is there (GNOME 3.26). Installed Fedora, GNOME works perfectly, despite being turned Hyper threading or not. I have no more ideas.