Comment # 1 on bug 911953 from Egbert Eich

s2ram is not the recommended way of suspending your system any more. Use 
'systemctl suspend' instead.
Still, can you get me /var/log/Xorg.0.log from your system pulled *after*
you've suspended and resumed it?
It could be that s2ram plays some games with udev so that the Xserver believes
it is seeing new input devices.