I briefly discussed the above log (output of "dmesg -w") on IRC with someone who seemed to have an understanding of the issue. They pointed out something important which I thought to highlight: The problem appears to start from 'radeon_vm_bo_invalidate' and is most likely a GPU locking bug. Looking at the stack trace I can see it, alongside explicit mentions of spin lock / CPU soft lockup / stall on CPU. I've also noticed a potentially important message, which although marked as a warning seems to point to a line of source code from the radeon driver: [58857.640890] WARNING: CPU: 3 PID: 2549 at ../drivers/gpu/drm/radeon/radeon_object.c:84 radeon_ttm_bo_destroy+0xec/0xf0 [radeon]