Regular 15.4, KDE, pulseaudio. I've not seen any other applications that have
audio problems

lincity-ng crashes because of sound:

robert@big:~> lincity-ng 
Starting lincity-ng (version 2.9.beta)...
[/home/robert/.lincity-ng] is in the search path.
[/home/robert/.lincity] is in the search path.
[/usr/share/lincity-ng] is in the search path.
[/home/robert/.lincity-ng] is the write directory.
Language is "de_DE".
 fast = 9

OpenGL Mode 3840x2160
File found: 'music/default/default.xml'. Loading song data...
Found song: 'Robert van Herk - City Blues'
Found song: 'Robert van Herk - Architectural Contemplations'
Found song: 'Pronobozo - Lincity'
lincity-ng: symbol lookup error: lincity-ng: undefined symbol: Mix_PlayChannel

It works however when started with "-m" for mute or with the right settings in
userconfig.xml. It will crash immediately when sound is enabled from the
options menu, with the above console output.