I just digged the internet a bit, and probably found a work-around. After 50 minutes that my system was totally irresponsive and 100% of one CPU time was consumed by btrfs-cleaner, I tried "btrfs quota disable /" and the system immediately returned to a normal work. goblin:~ # btrfs qgroup show / WARNING: qgroup data inconsistent, rescan recommended qgroupid rfer excl -------- ---- ---- 0/5 16.00KiB 16.00KiB 0/256 16.00KiB 16.00KiB 0/258 36.36GiB 36.36GiB 0/259 16.00KiB 16.00KiB 0/260 16.93MiB 16.93MiB 0/261 16.00KiB 16.00KiB 0/262 60.09MiB 60.09MiB 0/263 208.97MiB 208.97MiB 0/264 3.41MiB 3.41MiB 0/265 16.00KiB 16.00KiB 0/266 1.68MiB 1.68MiB 0/267 171.24GiB 481.68MiB 0/568 207.82GiB 1.33GiB 0/570 207.89GiB 598.05MiB 0/580 208.44GiB 40.92MiB 0/581 16.00KiB 16.00KiB 0/582 208.48GiB 20.84MiB 0/608 164.04GiB 76.45MiB 0/609 163.75GiB 86.62MiB 0/620 164.38GiB 35.93MiB 0/623 164.51GiB 207.21MiB 0/676 171.32GiB 932.00KiB 0/677 171.32GiB 804.00KiB 0/678 171.32GiB 672.00KiB 0/679 171.32GiB 932.00KiB 0/680 171.32GiB 624.00KiB 0/681 171.32GiB 1.28MiB 0/682 171.38GiB 876.00KiB 0/683 171.38GiB 1.54MiB 0/685 171.38GiB 596.00KiB 0/686 171.39GiB 3.06MiB 1/0 227.40GiB 56.04GiB 255/581 16.00KiB 16.00KiB goblin:~ # btrfs quota disable / goblin:~ # btrfs qgroup show / ERROR: can't list qgroups: quotas not enabled