It seems not hardware related. It happened mostly on three machines and for some others very sporadically. It seems more related to I/O (mainly NFS) or frequent remote logins (main differences to other servers/machines). This was all with systemd-208. Here the info for the three machines: Hardware name: ASUSTek Computer INC. RS300-E7-PS4/P8B-E Series, BIOS 5008 10/24/2012 CPU: Intel(R) Xeon(R) CPU E3-1270 V2 @ 3.50GHz Stepping: 9 Hardware name: Supermicro H8DGU/H8DGU, BIOS 1.0a 07/01/2010 CPU: AMD Opteron(tm) Processor 6136 Stepping: 1 Hardware name: Dell Inc. Precision WorkStation 390 /0DN075, BIOS 2.0.8 10/24/2006 CPU: Intel(R) Core(TM)2 CPU 6600 @ 2.40GHz Stepping: 6 With systemd-210 I have seen it only once until now.