The trackpad on my Framework Gen 11 laptop stopped working after a
suspend/resume cycle. The problem turned out to be that I had accidentally
enabled secure boot:

  Jun 06 19:18:01 homelap8.WalkerStreet.info kernel: mousedev: PS/2 mouse
device common for all mice
  Jun 06 19:18:05 homelap8.WalkerStreet.info kernel: Lockdown: vmmouse_detect:
raw io port access is restricted; see man kernel_lockdown.7

Disabling secure boot fixes the trackpad problem and eliminates the lockdown
log message. It looks like there's some issue in mousedev when secure boot is
enabled.