Yesterday I upgraded to TW 20201129 and there where still lockups. I googled around and found this link: https://linuxreviews.org/Linux_5.9_Is_Released_With_New_Drivers,_Improved_AMD_GPU_Support,_And_Support_The_x86-64_FSGSBASE_CPU_Instructions#Intel's_Also_In_The_GPU_Game_Now I started reading and there is ahci.mobile_lpm_policy=1 and intel_idle.max_cstate=1. I rebooted with those statements. Now I've been running 5.9.10 for 1.5h and no lockups. I'm not sure if both statements are needed. Will try later when everything seems stable enough.