I looked through the failure log file, but this didn't give any insights. What I found so far is that the device sends an interrupt request before any IRQs have been configured by the device driver. The IOMMU is configured to still block all interrupt requests from the device. This is the only situation where this can happen (in fact, when IV=1b and IntCtl=00b in the DTE for the device) As there are no AMD IOMMU changes in the range, my guess is that some other change between 5.14.2 and 5.14.4 influenced the behaviour of the Nvidia module, so that it now sends an IRQ when it really shouldn't. There are two options on how to proceed: * Bisect upstream stable kernels between 5.13.2 and 5.13.4 to find the commit which introduced the issue * Work around the problem by booting with 'intremap=off' on the kernel command line. Please let me know what you prefer.