When I start up my X session, pulseaudio is usually running and jackdbus, but neither connected to the hardware. I usually see the issue when I run "jack_control start" to start jack (which then bridges to pulse audio). Or if I stop the jack server or kill jackdbus (which sometimes hangs). What I just noticed is that pipewire was also running in the background. I was not even aware that I had it running on this system and strange because usually pipewire and pulse do not play well together. I have disabled the pipewire service now and will see if the issue seems to go away. But if you need me to reproduce let me know.