Hello, now I rebooted again without any updates. And after reboot I again can't access USB passthrough. Seems I have to apply your script every time I have to access USB... :-) Anyway, here are the outputs from your commands: the last line in /etc/group is: users:x:100:johannes johannes@JohannesOffice:~> ls -l /dev/bus/ insgesamt 0 drwxr-xr-x 8 root root 160 2020-07-30 20:59 usb johannes@JohannesOffice:~> johannes@JohannesOffice:~> ls -l /dev/bus/usb/ insgesamt 0 drwxr-xr-x 2 root root 120 2020-07-30 20:59 001 drwxr-xr-x 2 root root 60 2020-07-30 20:59 002 drwxr-xr-x 2 root root 100 2020-07-30 20:59 003 drwxr-xr-x 2 root root 100 2020-07-30 20:59 004 drwxr-xr-x 2 root root 60 2020-07-30 20:59 005 drwxr-xr-x 2 root root 60 2020-07-30 20:59 006 johannes@JohannesOffice:~> tail -f /var/log/Xorg.0.log [ 14.429] (II) AMDGPU(0): Modeline "1024x768"x0.0 65.00 1024 1048 1184 1344 768 771 777 806 -hsync -vsync (48.4 kHz e) [ 15.715] (II) AMDGPU(0): EDID vendor "ENC", prod id 5929 [ 15.715] (II) AMDGPU(0): Using hsync ranges from config file [ 15.715] (II) AMDGPU(0): Using vrefresh ranges from config file [ 15.715] (II) AMDGPU(0): Printing DDC gathered Modelines: [ 15.715] (II) AMDGPU(0): Modeline "1280x1024"x0.0 108.00 1280 1328 1440 1688 1024 1025 1028 1066 +hsync +vsync (64.0 kHz eP) [ 15.715] (II) AMDGPU(0): Modeline "800x600"x0.0 40.00 800 840 968 1056 600 601 605 628 +hsync +vsync (37.9 kHz e) [ 15.715] (II) AMDGPU(0): Modeline "640x480"x0.0 25.18 640 656 752 800 480 490 492 525 -hsync -vsync (31.5 kHz e) [ 15.715] (II) AMDGPU(0): Modeline "720x400"x0.0 28.32 720 738 846 900 400 412 414 449 -hsync +vsync (31.5 kHz e) [ 15.715] (II) AMDGPU(0): Modeline "1024x768"x0.0 65.00 1024 1048 1184 1344 768 771 777 806 -hsync -vsync (48.4 kHz e) ^C