I've taken a staging project and extracted which packages have issues with dwz:

WARNING:kernel-vanilla.log:[ 4429s] dwz: Multi-file optimization not allowed
for differentpointer sizes or endianity
WARNING:rubygem-nokogiri.log:[   76s] dwz:
./usr/lib64/ruby/gems/2.5.0/extensions/x86_64-linux/2.5.0/nokogiri-1.8.4/nokogiri/nokogiri.so-1.8.4-3.6.x86_64.debug:
DWARF version 0 unhandled
WARNING:go1.7.log:[  173s] dwz: .dwz/go1.7-1.7.5-10.3.x86_64: .debug_line
reference above end of section
WARNING:texlive.log:[ 1639s] dwz:
./usr/bin/pmxab-2018.20180414-55.3.x86_64.debug: Invalid DW_AT_decl_file file
number 2
WARNING:texlive.log:[ 1651s] dwz:
./usr/bin/scor2prt-2018.20180414-55.3.x86_64.debug: Invalid DW_AT_decl_file
file number 2
WARNING:inkscape.log:[ 1322s] dwz:
./usr/lib64/libinkscape_base.so-0.92.3-5.6.x86_64.debug: Couldn't find DIE
referenced by DW_OP_GNU_parameter_ref
WARNING:gcc8.log:[ 4227s] dwz: Multi-file optimization not allowed for
differentpointer sizes or endianity
WARNING:rubygem-byebug.log:[   79s] dwz:
./usr/lib64/ruby/gems/2.5.0/extensions/x86_64-linux/2.5.0/byebug-10.0.2/byebug/byebug.so-10.0.2-2.5.x86_64.debug:
DWARF version 0 unhandled
WARNING:java-1_8_0-openjdk.log:[ 1724s] dwz:
./usr/lib64/jvm/java-1.8.0-openjdk-1.8.0/jre/lib/amd64/server/libjvm.so-1.8.0.171-2.17.x86_64.debug:
Couldn't find DIE referenced by DW_OP_GNU_parameter_ref
WARNING:rubygem-unf_ext.log:[   48s] dwz:
./usr/lib64/ruby/gems/2.5.0/extensions/x86_64-linux/2.5.0/unf_ext-0.0.7.5/unf_ext.so-0.0.7.5-2.9.x86_64.debug:
DWARF version 0 unhandled
WARNING:valgrind.log:[  211s] dwz: Multi-file optimization not allowed for
differentpointer sizes or endianity
WARNING:pkg-config.log:[   77s] dwz: Too few files for multifile optimization
WARNING:rubygem-ruby-augeas.log:[   93s] dwz:
./usr/lib64/ruby/gems/2.5.0/extensions/x86_64-linux/2.5.0/ruby-augeas-0.5.0/_augeas.so-0.5.0-4.24.x86_64.debug:
DWARF version 0 unhandled
WARNING:libnumbertext.log:[   62s] dwz: .dwz/libnumbertext-1.0.2-3.6.x86_64:
.debug_info section not present
WARNING:uuid.log:[   68s] dwz: .dwz/uuid-1.6.2-21.79.x86_64: .debug_info
section not present
WARNING:MozillaFirefox.log:[ 3682s] dwz:
./usr/lib64/firefox/libxul.so-61.0.1-2.11.x86_64.debug: Too many DIEs, not
optimizing
WARNING:ruby2.5.log:[  522s] dwz:
./usr/lib64/libruby2.5.so.2.5.0-2.5.0-5.61.x86_64.debug: DWARF version 0
unhandled
WARNING:ruby2.5.log:[  522s] dwz:
./usr/lib64/ruby/2.5.0/x86_64-linux-gnu/racc/cparse.so-2.5.0-5.61.x86_64.debug:
DWARF version 0 unhandled
WARNING:ruby2.5.log:[  523s] dwz:
./usr/lib64/ruby/2.5.0/x86_64-linux-gnu/dbm.so-2.5.0-5.61.x86_64.debug: DWARF
version 0 unhandled
WARNING:ruby2.5.log:[  523s] dwz: Too few files for multifile optimization
WARNING:rrdtool.log:[  149s] dwz:
./usr/lib64/ruby/site_ruby/2.5.0/x86_64-linux-gnu/RRD.so-1.7.0-7.10.x86_64.debug:
DWARF version 0 unhandled
WARNING:qt4-qtscript.log:[  444s] dwz:
./usr/lib64/qt4/plugins/script/libqtscript_gui.so.1.0.0-0.2.0-14.5.x86_64.debug:
Couldn't find DIE referenced by DW_OP_GNU_parameter_ref
WARNING:gavl.log:[  104s] dwz: .dwz/gavl-1.4.0rsvn4256-3.5.x86_64: .debug_info
section not present
WARNING:MozillaThunderbird.log:[ 4660s] dwz:
./usr/lib64/thunderbird/libxul.so-52.9.1-2.10.x86_64.debug: Too many DIEs, not
optimizing
WARNING:libb64.log:[   60s] dwz: .dwz/libb64-1.2.1-3.5.x86_64: .debug_info
section not present
WARNING:containerd.log:[   94s] dwz: dwz.c:1985: checksum_die: Assertion
`((!op_multifile && !rd_multifile && !fi_multifile) || cu != die_cu (ref)) &&
(!op_multifile || cu->cu_chunk == die_cu (ref)->cu_chunk)' failed.
WARNING:kernel-debug.log:[ 4316s] dwz: Multi-file optimization not allowed for
differentpointer sizes or endianity
WARNING:cmake.log:[  684s] dwz: Too few files for multifile optimization
WARNING:libmypaint.log:[   70s] dwz: .dwz/libmypaint-1.3.0-2.5.x86_64:
.debug_info section not present
WARNING:go1.8.log:[  266s] dwz: .dwz/go1.8-1.8.7-2.3.x86_64: .debug_line
reference above end of section
WARNING:kernel-default.log:[ 2342s] dwz: Multi-file optimization not allowed
for differentpointer sizes or endianity
WARNING:virtualbox.log:[ 3394s] dwz:
./usr/lib/virtualbox/VirtualBox.so-5.2.16-2.4.x86_64.debug: Couldn't find DIE
referenced by DW_OP_GNU_parameter_ref
WARNING:mono-core.log:[ 3234s] dwz: .dwz/mono-core-5.10.1-2.17.x86_64:
.debug_line reference above end of section
WARNING:docker.log:[  308s] dwz: dwz.c:1985: checksum_die: Assertion
`((!op_multifile && !rd_multifile && !fi_multifile) || cu != die_cu (ref)) &&
(!op_multifile || cu->cu_chunk == die_cu (ref)->cu_chunk)' failed.
WARNING:gcc7.log:[ 2716s] dwz: Multi-file optimization not allowed for
differentpointer sizes or endianity