There is a second sound device associated with my graphics card; this device is not being used (it is disabled in YaST). Rollback to an older version of TW (with a 5.16.x kernel) failed to resolve the problem, however a complete power down (with power isolation to ensure that capacitors are discharged) *did* result in the sound functionality being restored. It looks like the kernel reboot I performed after the last TW update left the sound device in an inconsistent state which the kernel did not reset when booted. Based on this I guess you can close the bug report, at least until I can isolate things more comprehensively.