With all 32-bit compatibility libraries for Pulse installed, certain 32-bit
applications will not produce audio through Pulse. Turning off Pulse and
setting up Alsa with dmix remedies this, but this isn't ideal. Attempting to
run these programs with padsp will produce errors regarding the architecture
being wrong. While there is a libpulsedsp.so in /usr/lib64/pulseaudio, there
isn't one in /usr/lib/pulseaudio.

I came across this due to a good number of games purchased through Steam whose
Linux ports failed to produce sound. For some people who had this problem
(using certain other distributions of Linux), installing the 32-bit libraries
remedied this. For others, including myself, it did not, and it appears that
what is missing is that 32-bit version of libpulsedsp.so, which I presume is
provided in the packages of the distributions in which that fix works.